Goldmann Tonometry and Corneal Biomechanics

Glaucoma is the second cause of irreversible blindness in world. Intraocular pressure (IOP) a recognized major risk factor for development and progression glaucomatous damage. Goldmann applanation tonometry (GAT) internationally accepted as gold standard measurement IOP. The purpose this study was to search correlations between corneal mechanical properties thickness by means vitro tests. IOP measured tonometer (GIOP), transducer inserted anterior chamber eye (TIOP), at increasing levels addition saline solution enucleated pig eyes (n = 49). Mechanical were also determined inflation GAT underestimated real measurements made transducer, with most common differences range 15–28 mmHg. difference two instruments, highlighted Bland–Altman test, confirmed ANOVA, normality tests, Mann–Whitney’s both on data arranged infusions organized ranges. Pearson correlation tests revealed negative (TIOP-GIOP) stiffness thickness. In conclusion, obtained showed discrepancy GIOP TIOP more evident softer thinner corneas, that very important glaucoma detection.